BDBM409472 1-[6-[3-(Difluoromethyl)phenyl]-3-fluoro-pyrrolo[3,2-b]pyridin-1-::US10377753, Example 337

SMILES CCC(=O)Cn1cc(F)c2ncc(cc12)-c1cccc(c1)C(F)F

InChI Key InChIKey=AYNZKPMWQUXKCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409472   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409472(1-[6-[3-(Difluoromethyl)phenyl]-3-fluoro-pyrrolo[3...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent