BDBM409519 2-[3-Chloro-6-(4-fluorophenyl)pyrrolo[3,2-b]pyridin-1-yl]-1-::US10377753, Example 384

SMILES Fc1ccc(cc1)-c1cnc2c(Cl)cn(CC(=O)C3CC3)c2c1

InChI Key InChIKey=RZSODXIKNLOWNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409519   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409519(2-[3-Chloro-6-(4-fluorophenyl)pyrrolo[3,2-b]pyridi...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent