BDBM410056 D2198::US10370360, Example 8

SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)c(Cl)c(c1)C(F)(F)F)c1cncnc1

InChI Key InChIKey=KZJMAYVZYCIFHX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 410056   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410056(D2198 | US10370360, Example 8)
Affinity DataIC50:  65.9nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410056(D2198 | US10370360, Example 8)
Affinity DataIC50: >1.00E+4nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410056(D2198 | US10370360, Example 8)
Affinity DataIC50: >1.00E+4nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410056(D2198 | US10370360, Example 8)
Affinity DataIC50:  915nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent