BDBM410087 N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-((5-(thiazol-5-yl)pyridin-2-yl)methyl)chroman-7-yl)benzamide::US10370368, Example 4

SMILES CC(C)(C)S(=O)(=O)NC(=O)c1ccccc1-c1ccc2[C@H](O)[C@@H](Cc3ccc(cn3)-c3cncs3)COc2c1

InChI Key InChIKey=VNCCZLNDIWPBBX-CCLHPLFOSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410087   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410087(N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-...)
Affinity DataEC50:  8nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent