BDBM412081 US10392391, Compound I-G-54::US10787452, Compound I-G-54::US11117900, Compound I-G-54::US11370798, Cmpd. # I-G-54::US20230271963, Compound I-G-54
SMILES CN1CCN(CC1)C(=O)C1(C)CCN(CC1)c1c(F)cncc1NC(=O)c1c(N)nn2cc(F)cnc12
InChI Key InChIKey=QXAJJNLAKSOMHC-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 412081
Affinity DataKi: 505nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 505nMAssay Description:Assays were carried out at 25° C. in the presence of 5 nM full-length ATR. An assay stock buffer solution was prepared containing all of the reagents...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 505nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 550nMAssay Description:Table 5: Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out i...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 3.00E+3nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand Info