BDBM412228 (5S,6S)-6-(4,4- difluorocyclohexyl)-5- (4-(2-(3- (fluoromethyl)azetidin- 1-yl)ethoxy)phenyl)- 5,6,7,8- tetrahydronaphthalen- 2-ol::US10399939, Example 108

SMILES Oc1ccc2[C@@H]([C@@H](CCc2c1)C1CCC(F)(F)CC1)c1ccc(OCCN2CC(CF)C2)cc1

InChI Key InChIKey=DAMMPQHGQFGDAE-AHKZPQOWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412228   

TargetEstrogen receptor(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM412228((5S,6S)-6-(4,4- difluorocyclohexyl)-5- (4-(2-(3- (...)
Affinity DataEC50:  14.6nMAssay Description:The relative efficacies of Formula I compounds as inhibitors of an enzyme activity (or other biological activity) can be established by determining t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent