BDBM412693 2,3-Dimethyl-5- ((1-methyl-4- phenyl-1H- imidazol-2- yl)ethynyl)pyrazolo [1,5-a]pyrimidine::US10399985, Example 4

SMILES Cc1nn2ccc(nc2c1C)C#Cc1nc(cn1C)-c1ccccc1

InChI Key InChIKey=AABMZOLAKPRGCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412693   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM412693(2,3-Dimethyl-5- ((1-methyl-4- phenyl-1H- imidazol-...)
Affinity DataIC50:  1.5nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent