BDBM412697 2-Cyclopropyl-3- methyl-6-((1- methyl-4-phenyl- 1H-imidazol-2- yl)ethynyl)imidazo [1,2-b]pyridazine::US10399985, Example 10

SMILES Cc1c(nc2ccc(nn12)C#Cc1nc(cn1C)-c1ccccc1)C1CC1

InChI Key InChIKey=XQTYZTGFLQESCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412697   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM412697(2-Cyclopropyl-3- methyl-6-((1- methyl-4-phenyl- 1H...)
Affinity DataIC50:  12nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent