BDBM412698 (E)-2,3-Dimethyl-6-(2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)vinyl)imidazo[1,2-b]pyridazine::US10399985, Example 11

SMILES Cc1nc2ccc(\C=C\c3nc(nn3C)-c3ccccc3)nn2c1C

InChI Key InChIKey=CQODFSAPQHDBHP-PKNBQFBNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412698   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM412698((E)-2,3-Dimethyl-6-(2-(1-methyl-3-phenyl-1H-1,2,4-...)
Affinity DataIC50:  1.30nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent