BDBM412699 (E)-3-methyl-6-(2-(1- methyl-4-phenyl-1H- imidazol-2- yl)vinyl)imidazo[1,2- b]pyridazine-2- carbonitrile::US10399985, Example 12

SMILES Cc1c(nc2ccc(\C=C\c3nc(cn3C)-c3ccccc3)nn12)C#N

InChI Key InChIKey=YQFNYABJOFIGTC-CSKARUKUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412699   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM412699((E)-3-methyl-6-(2-(1- methyl-4-phenyl-1H- imidazol...)
Affinity DataIC50:  13.8nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent