BDBM412723 3-Methyl-6-((1-methyl- 4-phenyl-1H-imidazol- 2-yl)methoxy)-2- (trifluorome- thyl)imidazo[1,2- b]pyridazine::Roche-Dataset for PDE10A, Compound 305::US10399985, Example 36
SMILES Cc1c(nc2ccc(OCc3nc(cn3C)-c3ccccc3)nn12)C(F)(F)F
InChI Key InChIKey=OCUTYDYCRSAHIZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 412723
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 34nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 34.6nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
Ligand Info