BDBM412747 2-(6-(difluoromethyl)pyridin-2-yl)-4-(1H-pyrrolo[3,2-c]pyridin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine::US10399987, Example 12
SMILES FC(F)c1cccc(n1)-c1nc(-n2ccc3cnccc23)c2cc[nH]c2n1
InChI Key InChIKey=NHXWKPGFUOSQCJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 412747
Affinity DataIC50: 590nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.640nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info