BDBM414004 US10421760, Compound 15

SMILES C=CC(=O)NC1CCCC(=C1)c1ncnc2[nH]cc(-c3ccco3)c12

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 414004   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50:  2.60E+3nMAssay Description:JAK 1: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50:  0.330nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414004(US10421760, Compound 15)
Affinity DataIC50:  450nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent