BDBM414486 N-Ethyl-4-fluoro-N- {2-[4-(1-hydroxy-1- methylethyl)-5- methyl-1,3-oxazol- 2-yl]ethyl}-2-(2H- 1,2,3-triazol-2- yl)benzamide::US10435398, Example 4

SMILES CCN(CCc1nc(c(C)o1)C(C)(C)O)C(=O)c1ccc(F)cc1-n1nccn1

InChI Key InChIKey=DRBDZNVQBNDGQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414486   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414486(N-Ethyl-4-fluoro-N- {2-[4-(1-hydroxy-1- methylethy...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414486(N-Ethyl-4-fluoro-N- {2-[4-(1-hydroxy-1- methylethy...)
Affinity DataIC50:  48nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent