BDBM414504 2-(1-(difluoro- methyl)cyclopropyl)- N-ethyl-N-(2-(4-(2- hydroxypropan-2-yl)-5- methyloxazol-2- yl)ethyl)benzamide::US10435398, Example 18b

SMILES CCN(CCc1nc(c(C)o1)C(C)(C)O)C(=O)c1ccccc1C1(CC1)C(F)F

InChI Key InChIKey=DEZZUPOCYIPJSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414504   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414504(2-(1-(difluoro- methyl)cyclopropyl)- N-ethyl-N-(2-...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414504(2-(1-(difluoro- methyl)cyclopropyl)- N-ethyl-N-(2-...)
Affinity DataIC50:  145nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent