BDBM414511 N-(2,2-Difluoroethyl)-N-{2-[4-(1-hydroxy-1-methylethyl)-5-methyl-1,3-oxazol-2-yl]ethyl}-2-(2H-1,2,3-triazol-2-yl)benzamide::US10435398, Example 24

SMILES COC(=O)C(NC(=O)CCN(CC(F)F)C(=O)c1ccccc1-n1nccn1)C(C)=O

InChI Key InChIKey=PCTYSOAVNWMYAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414511   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414511(N-(2,2-Difluoroethyl)-N-{2-[4-(1-hydroxy-1-methyle...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414511(N-(2,2-Difluoroethyl)-N-{2-[4-(1-hydroxy-1-methyle...)
Affinity DataIC50:  68nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent