BDBM414517 N-Cyclopropyl-N-(2-(4-(2-hydroxypropan-2-yl)-5-methyloxazol-2-yl)ethyl)-2-(2H-1,2,3-triazol-2-yl)benzamide::US10435398, Example 31

SMILES COC(=O)C(NC(=O)CCN(C1CC1)C(=O)c1ccccc1-n1nccn1)C(C)=O

InChI Key InChIKey=BXYGJLJBMSSGFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414517   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414517(N-Cyclopropyl-N-(2-(4-(2-hydroxypropan-2-yl)-5-met...)
Affinity DataIC50:  7.59E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414517(N-Cyclopropyl-N-(2-(4-(2-hydroxypropan-2-yl)-5-met...)
Affinity DataIC50:  42nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent