BDBM414825 (6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-6a-hydroxy-2- methoxy-5,6,6a,7,7a,8,10a,11-octahydro- 6,11a-(epiminoethano)-naphtho[2,1- f]indol-9(10H)-one::US10435406, Compound 1
SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@@H]5NC(=O)C[C@@H]5C[C@@]34O)c2c1
InChI Key InChIKey=PNHRLHYXJJHZOE-UUIKSIEQSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414825
Affinity DataKi: 12.4nMAssay Description:Membranes from recombinantHEK-293 cells, CHO or U-2 OS cells expressing the recombinant human κ opioid receptor (κ) were prepared by lysing...More data for this Ligand-Target Pair
Affinity DataKi: 533nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair