BDBM414825 (6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-6a-hydroxy-2- methoxy-5,6,6a,7,7a,8,10a,11-octahydro- 6,11a-(epiminoethano)-naphtho[2,1- f]indol-9(10H)-one::US10435406, Compound 1

SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@@H]5NC(=O)C[C@@H]5C[C@@]34O)c2c1

InChI Key InChIKey=PNHRLHYXJJHZOE-UUIKSIEQSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414825   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM414825((6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-6a-...)
Affinity DataKi:  12.4nMAssay Description:Membranes from recombinantHEK-293 cells, CHO or U-2 OS cells expressing the recombinant human κ opioid receptor (κ) were prepared by lysing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM414825((6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-6a-...)
Affinity DataKi:  533nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent