BDBM414830 1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propionyl)-piperidine-4-carboxylic Acid Methyl-p-Tolyl-Amide::US10428024, Compound A1

SMILES CN(C(=O)C1CCN(CC1)C(=O)[C@@](C)(O)C(F)(F)F)c1ccc(C)cc1

InChI Key InChIKey=HNASDQTURQTLKS-QGZVFWFLSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414830   

LigandPNGBDBM414830(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataKd:  130nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM414830(1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...)
Affinity DataIC50:  1.10E+3nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent