BDBM415553 (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((R)-(3,4-difluorophenyl)(hydroxy)methyl)tetrahydrofuran-3,4-diol (LL-6)::US10428104, Example 84

SMILES CC1(C)O[C@@H]2[C@H](O[C@H]([C@@H]2O1)n1cnc2c(Cl)ncnc12)[C@H](O)c1ccc(F)c(F)c1

InChI Key InChIKey=JUZHNSYGAXEUOX-VFCJXBEMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415553   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM415553((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((R)-(3,...)
Affinity DataIC50:  3nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent