BDBM415584 (2R,3S,4R,5R)-2-((R)-(4-chloro-3-fluorophenyl)(hydroxy)methyl)-5-(7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (KKK-4)::US10428104, Example 115

SMILES O[C@@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2cncnc12)c1ccc(Cl)c(F)c1

InChI Key InChIKey=LFYVJIUIJXGCFE-JRBZFYFNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415584   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM415584((2R,3S,4R,5R)-2-((R)-(4-chloro-3-fluorophenyl)(hyd...)
Affinity DataIC50:  2nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent