BDBM415687 (S)-4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-indazol-3-yl]-5-methyl-5-{4-[2-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)ethyl]phenyl}-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one::US10428076, Example 256B
SMILES C[C@]1(C(=O)Nc2nc(ncc12)-c1nn(Cc2ccccc2F)c2cc(Cl)ccc12)c1ccc(CCc2noc(=O)[nH]2)cc1
InChI Key
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 415687
TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.0740nMAssay Description:The binding buffer was composed of 50 mM triethanolamine, pH 7.4, 3 mM MgCl2, 0.025% BSA, 2 mM dithiothreitol (DTT), 300 μM DETA/NO and 400 _...More data for this Ligand-Target Pair