BDBM415879 US10442772, Example 2-213-2

SMILES COC(=O)Cc1cc2nc(Nc3ccc(cc3)C(C)C)n([C@H]3C[C@@H](C)CC(C)(C)C3)c2cc1OC

InChI Key InChIKey=FYNJOIXOCAFMMF-XXBNENTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415879   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415879(US10442772, Example 2-213-2)
Affinity DataIC50:  10nMAssay Description:The biochemical reactions were performed at 32° C. in 384-well plates using a reaction volume of 41 μL and the following assay buffer conditions...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent