BDBM415919 US10442772, Example 2-233-2

SMILES CC(C)c1ccc(Nc2nc3cc(CCC(O)=O)ccc3n2[C@H]2CCCC(C)(C)C2)cc1

InChI Key InChIKey=VAHHCMLOSSLRAR-QFIPXVFZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415919   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415919(US10442772, Example 2-233-2)
Affinity DataIC50:  20nMAssay Description:The biochemical reactions were performed at 32° C. in 384-well plates using a reaction volume of 41 μL and the following assay buffer conditions...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent