BDBM416443 1-cyclopropyl-N-((R)-1-(4-(ethylsulfonyl)phenyl)-2-hydroxyethyl)-2-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide::US10301261, Compound AI-2
SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](CO)NC(=O)c1cnc2n(C3CC3)c(C[C@H]3CC[C@@H](CC3)C(F)(F)F)cc2c1
InChI Key InChIKey=YNDKPESMLXHPTG-DOPYIHRPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 416443
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted NanolucŪ luci...More data for this Ligand-Target Pair