BDBM416447 1-cyclopropyl-N-(4-(ethylsulfonyl)benzyl)-2-(((1r,4r)-4-(trifluoromethyl)cyclohexyl)oxy)-1H-benzo[d]imidazole-5-carboxamide::US10301261, Compound BE-3
SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(C4CC4)c(O[C@H]4CC[C@@H](CC4)C(F)(F)F)nc3c2)cc1
InChI Key InChIKey=YIDWXNZFSTWIHI-XUTJKUGGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 416447
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted NanolucŪ luci...More data for this Ligand-Target Pair