BDBM417218 US10457654, Example 87

SMILES CN(C)[C@H]1CC[C@@H](C[C@@H]1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=YYNPNJUJNNSTCY-JHVJFLLYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 417218   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM417218(US10457654, Example 87)
Affinity DataIC50:  0.539nMAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent