BDBM417390 US10457654, Example 242

SMILES Fc1cc(N[C@H]2CC[C@@H](C[C@@H]2N2CCCC2)c2cccc(c2)C(F)(F)F)c(Cl)cc1S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=GYRVYEANGPSPFD-OEOAZWSVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417390   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM417390(US10457654, Example 242)
Affinity DataIC50:  0.182nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM417390(US10457654, Example 242)
Affinity DataIC50:  0.428nMAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Following the procedure described in Example 243A, and making modificati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent