BDBM419868 US10464927, Compound I-16
SMILES CC(C)N1CCN(Cc2ccc(Nc3nccc(n3)-c3ccc4n(C)c(C)c(c4c3)C(F)(F)F)nc2)CC1
InChI Key InChIKey=ZAYBKFLWZSRLLN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 419868
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology
US Patent
Shanghai Xunhe Pharmaceutical Technology
US Patent
Affinity DataIC50: <20nMAssay Description:CDK6: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM D...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology
US Patent
Shanghai Xunhe Pharmaceutical Technology
US Patent
Affinity DataIC50: <20nMAssay Description:CDK4: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM DT...More data for this Ligand-Target Pair