BDBM419917 US10472364, Compound 3::US10472364, Compound 4::US11208414, Cpd. # 4

SMILES CCOC(=O)C(OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)n1cnc2c(NC(=O)OC(C)(C)C)nc(Cl)nc12)P(O)(O)=O

InChI Key InChIKey=DKFHRNGXPWDZQJ-ALQQZJTQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 419917   

Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419917(US10472364, Compound 3 | US10472364, Compound 4 | ...)
Affinity DataIC50:  2.47E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419917(US10472364, Compound 3 | US10472364, Compound 4 | ...)
Affinity DataIC50:  2.95E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419917(US10472364, Compound 3 | US10472364, Compound 4 | ...)
Affinity DataIC50:  2.47E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419917(US10472364, Compound 3 | US10472364, Compound 4 | ...)
Affinity DataIC50:  2.95E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent