BDBM419967 7-(3,5-dimethylisoxazol-4-yl)- 5-methyl-4-pyridin-2-yl-4,5- dihydroimidazo[1,5,4- de][1,4]benzoxazin-2(1H)-one::US10464947, Example 75

SMILES CC1Oc2c(cc(-c3ccccn3)c3[nH]c(=O)n(C1c1ccccn1)c23)-c1c(C)noc1C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419967   

TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM419967(7-(3,5-dimethylisoxazol-4-yl)- 5-methyl-4-pyridin-...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM419967(7-(3,5-dimethylisoxazol-4-yl)- 5-methyl-4-pyridin-...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent