BDBM421083 3-(8-aminoimidazo[1,2-a]pyrazin-3-yl)-N-((1- (cyclopropanecarbonyl)piperidin-4-yl)methyl)-4- methylbenzenesulfonamide::US10479795, Example 136::US10479795, Example 86

SMILES Cc1ccc(cc1-c1cnc2c(N)nccn12)S(=O)(=O)NCC1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=GHIUJAAQDZHNOS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 421083   

LigandPNGBDBM421083(3-(8-aminoimidazo[1,2-a]pyrazin-3-yl)-N-((1- (cycl...)
Affinity DataIC50: <100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM421083(3-(8-aminoimidazo[1,2-a]pyrazin-3-yl)-N-((1- (cycl...)
Affinity DataIC50: >2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM421083(3-(8-aminoimidazo[1,2-a]pyrazin-3-yl)-N-((1- (cycl...)
Affinity DataIC50: <500nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM421083(3-(8-aminoimidazo[1,2-a]pyrazin-3-yl)-N-((1- (cycl...)
Affinity DataIC50: <2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent