BDBM429818 Methyl (Z)-1-((4-(N-(3-bromo- 4-fluorophenyl)-N'- hydroxycarbamimidoyl)-1,2,5- oxadiazol-3- yl)thio)cyclobutane-1- carboxylate::US10538497, Example 21

SMILES COC(=O)C1(CCC1)Sc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=NEIXJTLKOAKNMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429818   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429818(Methyl (Z)-1-((4-(N-(3-bromo- 4-fluorophenyl)-N'- ...)
Affinity DataIC50:  5.90nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent