BDBM434079 US10562890, Compound Al-14-72

SMILES COc1ccnc(-c2nc3cc(OC(F)(F)F)ccc3[nH]2)c1OC

InChI Key InChIKey=GEHMQBZQTNRVSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 434079   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM434079(US10562890, Compound Al-14-72)
Affinity DataIC50:  1.72E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent