BDBM434541 US10562900, Example 19::US10562900, Example 36

SMILES COc1cc(OC)c(Cl)c(-c2ccc3c(NC(=O)c4ccc(cc4)N4CCN(CC4)C(C)=O)n[nH]c3c2)c1Cl

InChI Key InChIKey=DXNWONDDCYCQQB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 434541   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434541(US10562900, Example 19 | US10562900, Example 36)
Affinity DataIC50:  600nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434541(US10562900, Example 19 | US10562900, Example 36)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434541(US10562900, Example 19 | US10562900, Example 36)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434541(US10562900, Example 19 | US10562900, Example 36)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434541(US10562900, Example 19 | US10562900, Example 36)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434541(US10562900, Example 19 | US10562900, Example 36)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent