BDBM434548 US10562900, Example 26

SMILES COc1cc(OC)c(Cl)c(-c2ccc3c(NC(=O)c4ccc(NCCCN(C)C)cc4)n[nH]c3c2)c1Cl

InChI Key InChIKey=VWNGKPLSBPIROQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434548   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434548(US10562900, Example 26)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM434548(US10562900, Example 26)
Affinity DataIC50: <100nMAssay Description:The enzyme reaction substrate Poly(Glu,Tyr) 4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4) to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent