BDBM435237 N-(isoxazol-3-yl)-8-(((trans)-2-(3- methyl-1,2,4-oxadiazol-5- yl)cyclopropanecarboxamido)methyl)- 5-(3-(trifluoromethoxy)phenyl)-3,4- dihydroisoquinoline-2(1H)- carboxamide (mixture of 2 isomers)::US10568876, Example 2

SMILES Cc1noc(n1)[C@@H]1C[C@H]1C(=O)NCc1ccc(-c2cccc(OC(F)(F)F)c2)c2CCN(Cc12)C(=O)Nc1ccon1

InChI Key InChIKey=HMUNWSYQJVAIOP-FGZHOGPDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435237   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435237(N-(isoxazol-3-yl)-8-(((trans)-2-(3- methyl-1,2,4-o...)
Affinity DataIC50:  112nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent