BDBM435238 N-(tert-butyl)-8-(((trans)-2-(3-methyl- 1,2,4-oxadiazol-5- yl)cyclopropanecarboxamido)methyl)- 5-(3-(trifluoromethyl)phenyl)-3,4- dihydroisoquinoline-2(1H)- carboxamide (mixture of 2 isomers)::US10568876, Example 3

SMILES Cc1noc(n1)C1C[C@@H]1C(=O)NCc1ccc(-c2cccc(c2)C(F)(F)F)c2CCN(Cc12)C(=O)NC(C)(C)C

InChI Key InChIKey=IUSGTJJUMDUQLE-NQCNTLBGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435238   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435238(N-(tert-butyl)-8-(((trans)-2-(3-methyl- 1,2,4-oxad...)
Affinity DataIC50:  5.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent