BDBM435258 N-(tert-butyl)-5-(3-cyanophenyl)-8- (((trans)-2- phenylcyclopropanecarboxamido) methyl)-3,4-dihydroisoquinoline-2(1H)- carboxamide (mixture of 2 isomers)::US10568876, Example 22

SMILES CC(C)(C)NC(=O)N1CCc2c(C1)c(CNC(=O)[C@@H]1C[C@H]1c1ccccc1)ccc2-c1cccc(c1)C#N

InChI Key InChIKey=ZYLIHTNPAGUWJC-WUFINQPMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435258   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435258(N-(tert-butyl)-5-(3-cyanophenyl)-8- (((trans)-2- p...)
Affinity DataIC50:  16.1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent