BDBM435279 N-(tert-butyl)-5-(3-carbamoylphenyl)- 8-(((trans)-2- phenylcyclopropanecarboxamido) methyl)-3,4-dihydroisoquinoline-2(1H)- carboxamide (mixture of 2 isomers)::US10568876, Example 42

SMILES CC(C)(C)NC(=O)N1CCc2c(C1)c(CNC(=O)C1C[C@H]1c1ccccc1)ccc2-c1cccc(c1)C(N)=O

InChI Key InChIKey=QPAPNKHHBWZAAK-QBHOUYDASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435279   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435279(N-(tert-butyl)-5-(3-carbamoylphenyl)- 8-(((trans)-...)
Affinity DataIC50:  155nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent