BDBM435304 8-(((trans)-2-(3-methyl-1,2,4-oxadiazol-5- yl)cyclopropanecarboxamido)methyl)-N- (3-methyloxetan-3-yl)-5-(3- (trifluoromethoxy)phenyl)-3,4- dihydroisoquinoline-2(1H)-carboxamide (mixture of 2 isomers)::US10568876, Example 67
SMILES Cc1noc(n1)[C@@H]1C[C@H]1C(=O)NCc1ccc(-c2cccc(OC(F)(F)F)c2)c2CCN(Cc12)C(=O)NC1(C)COC1
InChI Key InChIKey=WPFOKKHNARTHKD-DHIUTWEWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 435304
Affinity DataIC50: 13.6nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair