BDBM435415 US10570116, Compound C23

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)COCc1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=UQSSCRPZDDBPIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435415   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM435415(US10570116, Compound C23)
Affinity DataIC50:  900nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF® (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM435415(US10570116, Compound C23)
Affinity DataIC50:  2.10nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM435415(US10570116, Compound C23)
Affinity DataIC50:  6.30nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent