BDBM436736 6-(2,4-Difluoro-3-methyl-phenyl)-3-methyl-1-(pyridazin-3- ylmethyl)imidazo[4,5-b]pyridin-2-one::US10617676, Example 67::US11207298, Example 67

SMILES Cc1c(F)ccc(c1F)-c1cnc2n(C)c(=O)n(Cc3cccnn3)c2c1

InChI Key InChIKey=UVXXMLSHLCDUMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436736   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436736(6-(2,4-Difluoro-3-methyl-phenyl)-3-methyl-1-(pyrid...)
Affinity DataIC50:  9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436736(6-(2,4-Difluoro-3-methyl-phenyl)-3-methyl-1-(pyrid...)
Affinity DataIC50:  9nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent