BDBM436768 6-[5-(Difluoromethyl)-3-thienyl]-1-[2-(3-fluoroazetidin-1-yl)-2-oxo-ethyl]-3- methyl-imidazo[4,5-b]pyridin-2-one::US10617676, Example 99::US11207298, Example 99

SMILES Cn1c2ncc(cc2n(CC(=O)N2CC(F)C2)c1=O)-c1csc(c1)C(F)F

InChI Key InChIKey=UCCDBFCIBNXQQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436768   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436768(6-[5-(Difluoromethyl)-3-thienyl]-1-[2-(3-fluoroaze...)
Affinity DataIC50:  7nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent