BDBM437773 US10597366, Compound 58

SMILES O[C@@H]1CCc2c1c(ccc2Oc1cc(F)cc(F)c1)C(F)(F)F

InChI Key InChIKey=WYQNGHURDXWRST-CYBMUJFWSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437773   

TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM437773(US10597366, Compound 58)
Affinity DataIC50: <5nMAssay Description:HIF-2a: The total assay volume was about 100 uL in the following configuration: 2 uL compound in 100% DMSO, 88 uL buffer with protein and probe and 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB