BDBM437896 (2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl)pyrimidin- 5-yl]-4-pyridyl]methyl]-3-(4- fluorophenyl)sulfonyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 24
SMILES FC(F)c1cnc(cc1CNC(=O)[C@@H]1C2CC(C2)N1S(=O)(=O)c1ccc(F)cc1)-c1cnc(nc1)C(F)(F)F
InChI Key InChIKey=JPKCFBGTYVDSPZ-AEABFECFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 437896
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 9.92nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair