BDBM438083 US10597366, Compound 338

SMILES NS(=O)(=O)c1ccc(Oc2cc(F)cc(c2)C#N)c2[C@@H](F)C(F)(F)[C@@H](O)c12

InChI Key InChIKey=FBVULQCFTKITLH-CABCVRRESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438083   

TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM438083(US10597366, Compound 338)
Affinity DataIC50:  13nMAssay Description:HIF-2a: The total assay volume was about 100 uL in the following configuration: 2 uL compound in 100% DMSO, 88 uL buffer with protein and probe and 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent