BDBM444814 US10662189, Compound WX065

SMILES CCOc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)n1c2nccc(-c3ccccc3F)c2nc1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444814   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Shijiazhuang Sagacity New Drug Development

US Patent
LigandPNGBDBM444814(US10662189, Compound WX065)
Affinity DataIC50:  8.80nMAssay Description:The enzyme activity was indicated by measuring the AMP/GMP expression and tracing AMP/GMP antibody binding based on fluorescence polarization in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Shijiazhuang Sagacity New Drug Development

US Patent
LigandPNGBDBM444814(US10662189, Compound WX065)
Affinity DataIC50:  1.87nMAssay Description:The enzyme activity was indicated by measuring the AMP/GMP expression and tracing AMP/GMP antibody binding based on fluorescence polarization in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent