BDBM445699 Ex. 35/KM-06-163/(I-35)::US10683309, Example 35::US11028104, Example 35

SMILES CCn1c2nc(Cc3cn4CCCCc4n3)n(Cc3ccc(NC(C)=O)cc3)c2c(=O)[nH]c1=O

InChI Key InChIKey=CGLOGXGDGPMEGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445699   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM445699(Ex. 35/KM-06-163/(I-35) | US10683309, Example 35 |...)
Affinity DataIC50:  286nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM445699(Ex. 35/KM-06-163/(I-35) | US10683309, Example 35 |...)
Affinity DataIC50:  286nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin

US Patent
LigandPNGBDBM445699(Ex. 35/KM-06-163/(I-35) | US10683309, Example 35 |...)
Affinity DataIC50:  36nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent