BDBM448197 US10689401, EX 4::US11008338, Example 4
SMILES CC(C)COc1ccc(F)c(c1)[C@]12CO[C@@H](C)C[C@H]1S(=O)(=O)C(C)(C)C(=N)N2
InChI Key InChIKey=QUQKAGGARNDCIR-WSXQUGQNSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 448197
Affinity DataKi: 31.6nMAssay Description:BACE-2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY...More data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:BACE2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7...More data for this Ligand-Target Pair
Affinity DataKi: 354nMAssay Description:BACE1: A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This a...More data for this Ligand-Target Pair
Affinity DataKi: 354nMAssay Description:BACE1: A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This a...More data for this Ligand-Target Pair